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ANALYSIS
OF HAV MOTIF |
Cadherins
have HAV motif in the first cadherin repeat that
is believe to be responsible for the specificity.
It might be interesting to see if this is conserved
in other families of cadherins. |
|
ANALYSIS
OF CALCIUM BINDING SITES |
Cadherins are a calcium dependent adhesion protein.
The calcium binding site is known for epithelial
cadherin. It might be interesting to find similar
sites in other cadherins.
|
|
COMPUTER
MODELING OF CADHERIN REPEAT |
We
are doing structural work in our lab to try to
find the mechanism of binding of epithelial cadherins.
When we have a structure, it would be interesting
to model other cadherins. It might give insights
on specificity and homophilic binding.
|
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OTHER
ANALYSIS |
|
Any
suggestions for interesting analysis? Please email
us.
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TOP
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